| 1 | Central Point city (south-southwest) | 7,354 |
| 2 | Medford city (west-northwest 2) | 7,075 |
| 3 | White City CDP (east-northeast) | 6,937 |
| 4 | Eagle Point city (north-northwest) | 6,359 |
| 5 | Medford city (northwest 2) | 5,923 |
| 6 | Phoenix city (northwest) | 5,914 |
| 7 | Medford city (north-northwest 3) | 5,803 |
| 8 | Medford city (north-northeast) | 5,802 |
| 9 | White City CDP (west-southwest) | 5,772 |
| 10 | Central Point city (south-southeast) | 5,753 |
| 11 | Central Point city (north-northwest) | 5,599 |
| 12 | Medford city (west-southwest) | 5,430 |
| 13 | Medford city (east-northeast) | 5,361 |
| 14 | Ashland city (south) | 5,125 |
| 15 | Jacksonville city | 5,068 |
| 16 | Ruch CDP | 5,015 |
| 17 | Medford city (southwest) | 4,927 |
| 18 | Medford city (north-northwest 2) | 4,805 |
| 19 | Central Point city (east) | 4,790 |
| 20 | Gold Hill city | 4,765 |
| 21 | Ashland city (east-southeast) | 4,683 |
| 22 | Medford city (north) | 4,630 |
| 23 | Medford city (north-northwest 1) | 4,414 |
| 24 | Medford city (east-southeast) | 4,404 |
| 25 | Medford city (northeast) | 4,381 |
| 26 | Talent city (northwest) | 4,375 |
| 27 | Trail CDP (west) | 4,151 |
| 28 | Foots Creek CDP | 4,054 |
| 29 | Medford city (west 2) | 4,012 |
| 30 | Ashland city (north) | 3,987 |
| 31 | Wimer CDP | 3,841 |
| 32 | Medford city (west-northwest 3) | 3,832 |
| 33 | Medford city (south-southeast 1) | 3,795 |
| 34 | Eagle Point city (south) | 3,771 |
| 35 | Medford city (south) | 3,718 |
| 36 | Medford city (west 1) | 3,634 |
| 37 | Ashland city (west-northwest) | 3,470 |
| 38 | Medford city (south-southeast 2) | 3,436 |
| 39 | Trail CDP (east) | 3,306 |
| 40 | Rogue River city | 3,212 |
| 41 | Medford city (west 3) | 3,140 |
| 42 | Medford city (northwest 1) | 3,103 |
| 43 | Ashland city (southeast) | 3,073 |
| 44 | Talent city (southeast) | 2,996 |
| 45 | Medford city (southeast) | 2,962 |
| 46 | Prospect CDP | 2,661 |
| 47 | Phoenix city (southeast) | 2,397 |
| 48 | Medford city (west-northwest 1) | 2,390 |
| 49 | Ashland city (north-northwest) | 2,286 |
| 50 | Medford city (south-southeast 3) | 2,078 |
| 51 | Unincorporated | 1,701 |
| 52 | Eagle Point city (north) | 1,093 |