| 1 | Unincorporated (east) | 8,150 |
| 2 | Unincorporated (north-northeast 7) | 7,376 |
| 3 | Hamburg village (northwest) | 7,265 |
| 4 | Unincorporated (northwest 2) | 7,034 |
| 5 | Orchard Park village (south-southeast) | 7,026 |
| 6 | Unincorporated (north 3) | 6,954 |
| 7 | Buffalo city (northeast 3) | 6,948 |
| 8 | Orchard Park village (south-southwest) | 6,884 |
| 9 | Unincorporated (north 8) | 6,587 |
| 10 | Orchard Park village (northwest) | 6,488 |
| 11 | Unincorporated (north 2) | 6,457 |
| 12 | Tonawanda Town CDP (northeast 1) | 6,443 |
| 13 | Unincorporated (east-northeast 1) | 6,434 |
| 14 | Buffalo city (south-southeast 4) | 6,360 |
| 15 | Unincorporated (north-northwest 1) | 6,311 |
| 16 | Hamburg village (west) | 6,304 |
| 17 | Tonawanda Town CDP (northwest) | 6,265 |
| 18 | Unincorporated (northwest 1) | 6,237 |
| 19 | Orchard Park village (north-northeast 2) | 6,234 |
| 20 | Wanakah CDP (east-northeast) | 6,169 |
| 21 | Town Line CDP (east) | 6,148 |
| 22 | Lancaster village (south) | 5,988 |
| 23 | Unincorporated (south-southwest 1) | 5,934 |
| 24 | Elma Center CDP (east) | 5,879 |
| 25 | University at Buffalo CDP (east-southeast) | 5,840 |
| 26 | Elma Center CDP (west) | 5,804 |
| 27 | Eggertsville CDP (east-northeast) | 5,763 |
| 28 | Unincorporated (north-northwest 2) | 5,732 |
| 29 | Tonawanda Town CDP (south-southeast) | 5,722 |
| 30 | Grandyle Village CDP (south-southeast) | 5,670 |
| 31 | Buffalo city (northwest 3) | 5,652 |
| 32 | Clarence Center CDP (north) | 5,652 |
| 33 | Williamsville village (northeast) | 5,495 |
| 34 | Billington Heights CDP | 5,447 |
| 35 | Hamburg village (east-southeast) | 5,362 |
| 36 | Tonawanda city (west) | 5,313 |
| 37 | Cheektowaga CDP (south-southeast 3) | 5,310 |
| 38 | Buffalo city (north-northeast 3) | 5,289 |
| 39 | Harris Hill CDP (south) | 5,268 |
| 40 | Unincorporated (east-southeast 2) | 5,258 |
| 41 | Buffalo city (north-northeast 5) | 5,226 |
| 42 | Unincorporated (east-southeast 1) | 5,169 |
| 43 | Tonawanda Town CDP (southeast 1) | 5,163 |
| 44 | Buffalo city (northwest 1) | 5,123 |
| 45 | Cheektowaga CDP (northwest) | 5,108 |
| 46 | Eggertsville CDP (south-southeast) | 5,107 |
| 47 | Clarence Center CDP (south) | 5,083 |
| 48 | Williamsville village (west-southwest) | 5,074 |
| 49 | West Seneca CDP (southwest) | 4,980 |
| 50 | West Seneca CDP (south-southeast) | 4,977 |
| 51 | Eggertsville CDP (west-northwest) | 4,971 |
| 52 | Kenmore village (west-northwest) | 4,933 |
| 53 | Tonawanda Town CDP (southeast 2) | 4,930 |
| 54 | Cheektowaga CDP (southeast 2) | 4,841 |
| 55 | Buffalo city (east-southeast 3) | 4,830 |
| 56 | Buffalo city (northeast 4) | 4,817 |
| 57 | North Boston CDP (east-northeast) | 4,814 |
| 58 | Buffalo city (north-northwest 3) | 4,800 |
| 59 | Buffalo city (south-southeast 7) | 4,787 |
| 60 | Unincorporated (east-northeast 2) | 4,764 |
| 61 | Harris Hill CDP (north) | 4,763 |
| 62 | Unincorporated (north-northeast 1) | 4,753 |
| 63 | West Seneca CDP (northeast) | 4,736 |
| 64 | Unincorporated (southwest 1) | 4,673 |
| 65 | Tonawanda city (northwest) | 4,659 |
| 66 | Buffalo city (northwest 6) | 4,652 |
| 67 | Wanakah CDP (west-southwest) | 4,601 |
| 68 | Buffalo city (north 2) | 4,589 |
| 69 | Buffalo city (south-southeast 1) | 4,571 |
| 70 | Eden CDP | 4,523 |
| 71 | Depew village (north) | 4,496 |
| 72 | Kenmore village (east-northeast) | 4,476 |
| 73 | Unincorporated (north 9) | 4,475 |
| 74 | Unincorporated (south-southwest 8) | 4,468 |
| 75 | Highland-on-the-Lake CDP (south-southwest) | 4,450 |
| 76 | Unincorporated (north 5) | 4,442 |
| 77 | Cheektowaga CDP (north-northwest 1) | 4,435 |
| 78 | West Seneca CDP (east-southeast) | 4,428 |
| 79 | Buffalo city (east 1) | 4,427 |
| 80 | West Seneca CDP (northwest 1) | 4,417 |
| 81 | Town Line CDP (west) | 4,411 |
| 82 | Lackawanna city (west) | 4,396 |
| 83 | Cheektowaga CDP (north-northwest 2) | 4,386 |
| 84 | Cheektowaga CDP (southeast 1) | 4,382 |
| 85 | Unincorporated (north-northeast 3) | 4,360 |
| 86 | Buffalo city (northwest 2) | 4,318 |
| 87 | Buffalo city (northwest 7) | 4,314 |
| 88 | Unincorporated (north-northeast 6) | 4,313 |
| 89 | Buffalo city (west-northwest 3) | 4,312 |
| 90 | Tonawanda Town CDP (northeast 2) | 4,305 |
| 91 | Williamsville village (southeast) | 4,299 |
| 92 | Buffalo city (north-northwest 2) | 4,289 |
| 93 | Unincorporated (north-northwest 4) | 4,259 |
| 94 | Buffalo city (south-southeast 10) | 4,252 |
| 95 | Buffalo city (west 7) | 4,209 |
| 96 | Cheektowaga CDP (south-southwest) | 4,205 |
| 97 | Springville village (southeast) | 4,196 |
| 98 | Buffalo city (north 1) | 4,183 |
| 99 | Lackawanna city (east-northeast) | 4,141 |
| 100 | Lancaster village (north) | 4,139 |
| 101 | Cheektowaga CDP (east-northeast) | 4,117 |
| 102 | Tonawanda Town CDP (south-southwest) | 4,114 |
| 103 | Buffalo city (east-northeast 1) | 4,092 |
| 104 | Springville village (northwest) | 4,079 |
| 105 | Buffalo city (north-northeast 7) | 4,070 |
| 106 | Buffalo city (north 6) | 4,061 |
| 107 | Clarence CDP | 4,013 |
| 108 | Unincorporated (north 4) | 4,004 |
| 109 | University at Buffalo CDP (west-northwest) | 4,003 |
| 110 | Unincorporated (north-northeast 2) | 3,971 |
| 111 | West Seneca CDP (west) | 3,962 |
| 112 | Cheektowaga CDP (south-southeast 1) | 3,919 |
| 113 | Buffalo city (north-northwest 5) | 3,882 |
| 114 | Cheektowaga CDP (north) | 3,874 |
| 115 | Unincorporated (north-northeast 4) | 3,836 |
| 116 | West Seneca CDP (east) | 3,788 |
| 117 | Buffalo city (northwest 9) | 3,780 |
| 118 | East Aurora village (north-northeast) | 3,770 |
| 119 | Sloan village | 3,757 |
| 120 | Buffalo city (southeast 5) | 3,745 |
| 121 | Lackawanna city (northwest) | 3,745 |
| 122 | Tonawanda Town CDP (west-southwest 1) | 3,745 |
| 123 | Depew village (east-northeast) | 3,725 |
| 124 | Buffalo city (northeast 1) | 3,712 |
| 125 | Unincorporated (south-southwest 5) | 3,687 |
| 126 | Buffalo city (west 2) | 3,665 |
| 127 | Akron village (south-southwest) | 3,648 |
| 128 | Buffalo city (north-northeast 2) | 3,610 |
| 129 | Unincorporated (north 6) | 3,601 |
| 130 | Buffalo city (south-southeast 2) | 3,578 |
| 131 | West Seneca CDP (south-southwest) | 3,563 |
| 132 | Buffalo city (northeast 6) | 3,547 |
| 133 | North Collins village | 3,503 |
| 134 | Buffalo city (southeast 4) | 3,392 |
| 135 | Cheektowaga CDP (northeast 1) | 3,376 |
| 136 | Buffalo city (west 1) | 3,367 |
| 137 | Kenmore village (west) | 3,358 |
| 138 | Cheektowaga CDP (northeast 2) | 3,343 |
| 139 | Buffalo city (north-northeast 6) | 3,339 |
| 140 | Eggertsville CDP (north-northwest) | 3,324 |
| 141 | Buffalo city (north 3) | 3,287 |
| 142 | Holland CDP | 3,278 |
| 143 | Buffalo city (south-southeast 5) | 3,276 |
| 144 | Buffalo city (northwest 8) | 3,263 |
| 145 | Buffalo city (east 4) | 3,253 |
| 146 | Lake Erie Beach CDP | 3,247 |
| 147 | Unincorporated (north 1) | 3,247 |
| 148 | Unincorporated (north 7) | 3,235 |
| 149 | Hamburg village (east) | 3,230 |
| 150 | Buffalo city (west 5) | 3,201 |
| 151 | Buffalo city (north 5) | 3,160 |
| 152 | North Boston CDP (west-southwest) | 3,137 |
| 153 | Unincorporated (south-southeast 2) | 3,132 |
| 154 | Buffalo city (south-southwest 5) | 3,093 |
| 155 | Tonawanda Town CDP (north-northeast) | 3,093 |
| 156 | Orchard Park village (north-northeast 1) | 3,092 |
| 157 | Tonawanda Town CDP (east 1) | 3,083 |
| 158 | Buffalo city (west-southwest 3) | 3,067 |
| 159 | Buffalo city (east 6) | 3,066 |
| 160 | Buffalo city (northeast 7) | 3,053 |
| 161 | Unincorporated (south-southwest 2) | 3,028 |
| 162 | Unincorporated (southeast) | 3,003 |
| 163 | Unincorporated (south-southwest 7) | 2,954 |
| 164 | Unincorporated (north 10) | 2,911 |
| 165 | Buffalo city (east-northeast 2) | 2,857 |
| 166 | Unincorporated (southwest 2) | 2,853 |
| 167 | Cheektowaga CDP (south-southeast 2) | 2,848 |
| 168 | Akron village (east) | 2,838 |
| 169 | Depew village (west-northwest) | 2,833 |
| 170 | Buffalo city (northeast 5) | 2,832 |
| 171 | Tonawanda city (east-southeast) | 2,797 |
| 172 | Tonawanda Town CDP (east 2) | 2,790 |
| 173 | Tonawanda Town CDP (west-northwest 1) | 2,737 |
| 174 | Unincorporated (south-southeast 1) | 2,714 |
| 175 | Highland-on-the-Lake CDP (north-northeast) | 2,700 |
| 176 | Lackawanna city (east-southeast 1) | 2,688 |
| 177 | West Seneca CDP (southeast) | 2,679 |
| 178 | Buffalo city (west-northwest 4) | 2,636 |
| 179 | Cheektowaga CDP (west-northwest 3) | 2,632 |
| 180 | Buffalo city (south 2) | 2,631 |
| 181 | Angola village | 2,628 |
| 182 | Cheektowaga CDP (west-northwest 2) | 2,627 |
| 183 | Buffalo city (east-northeast 3) | 2,625 |
| 184 | Buffalo city (southeast 6) | 2,607 |
| 185 | Buffalo city (south-southeast 11) | 2,605 |
| 186 | Alden village | 2,595 |
| 187 | Unincorporated (south-southwest 4) | 2,581 |
| 188 | Blasdell village | 2,534 |
| 189 | Buffalo city (east 5) | 2,501 |
| 190 | Grandyle Village CDP (north-northwest) | 2,500 |
| 191 | Cheektowaga CDP (southwest 2) | 2,479 |
| 192 | West Seneca CDP (west-northwest 1) | 2,476 |
| 193 | Buffalo city (west-northwest 1) | 2,467 |
| 194 | Lackawanna city (southwest) | 2,460 |
| 195 | Cheektowaga CDP (north-northwest 4) | 2,429 |
| 196 | Buffalo city (west 3) | 2,427 |
| 197 | East Aurora village (south-southwest) | 2,422 |
| 198 | Tonawanda Town CDP (west-southwest 2) | 2,415 |
| 199 | Buffalo city (northwest 4) | 2,412 |
| 200 | Cheektowaga CDP (north-northwest 3) | 2,367 |
| 201 | Buffalo city (north-northwest 1) | 2,361 |
| 202 | Lackawanna city (east-southeast 2) | 2,349 |
| 203 | Buffalo city (southwest 2) | 2,347 |
| 204 | Kenmore village (east-southeast) | 2,330 |
| 205 | Buffalo city (northeast 2) | 2,317 |
| 206 | Buffalo city (west-southwest 4) | 2,307 |
| 207 | Buffalo city (southwest 4) | 2,275 |
| 208 | Tonawanda city (east-northeast) | 2,275 |
| 209 | Buffalo city (south-southwest 1) | 2,256 |
| 210 | Cheektowaga CDP (west) | 2,252 |
| 211 | Buffalo city (south-southeast 3) | 2,246 |
| 212 | Unincorporated (north-northwest 3) | 2,240 |
| 213 | Unincorporated (south-southeast 3) | 2,231 |
| 214 | Angola on the Lake CDP | 2,211 |
| 215 | Akron village (north) | 2,197 |
| 216 | Farnham village | 2,169 |
| 217 | Tonawanda Town CDP (west-northwest 2) | 2,168 |
| 218 | Depew village (southeast) | 2,158 |
| 219 | Buffalo city (south-southeast 8) | 2,140 |
| 220 | Buffalo city (southwest 3) | 2,121 |
| 221 | Buffalo city (west-northwest 2) | 2,115 |
| 222 | Buffalo city (east-southeast 2) | 2,099 |
| 223 | Cheektowaga CDP (southwest 1) | 2,062 |
| 224 | West Seneca CDP (northwest 2) | 2,061 |
| 225 | Buffalo city (north-northwest 4) | 2,051 |
| 226 | Buffalo city (south-southwest 3) | 2,048 |
| 227 | Cheektowaga CDP (east-southeast) | 2,046 |
| 228 | Buffalo city (south-southeast 6) | 2,044 |
| 229 | Buffalo city (west 6) | 1,993 |
| 230 | Buffalo city (southeast 1) | 1,982 |
| 231 | Buffalo city (southeast 2) | 1,920 |
| 232 | Cheektowaga CDP (southwest 3) | 1,892 |
| 233 | West Seneca CDP (east-northeast) | 1,888 |
| 234 | Unincorporated (south-southwest 3) | 1,868 |
| 235 | Depew village (south-southwest) | 1,853 |
| 236 | Buffalo city (south 1) | 1,817 |
| 237 | Buffalo city (south-southwest 4) | 1,799 |
| 238 | Gowanda village | 1,763 |
| 239 | Buffalo city (northwest 5) | 1,744 |
| 240 | Buffalo city (west 4) | 1,726 |
| 241 | Buffalo city (north 7) | 1,658 |
| 242 | Buffalo city (north 4) | 1,577 |
| 243 | Buffalo city (east 2) | 1,558 |
| 244 | Buffalo city (east 3) | 1,552 |
| 245 | Buffalo city (west-southwest 2) | 1,513 |
| 246 | Unincorporated (north-northeast 5) | 1,465 |
| 247 | Buffalo city (west-southwest 1) | 1,460 |
| 248 | Buffalo city (southeast 3) | 1,449 |
| 249 | Buffalo city (west-southwest 5) | 1,446 |
| 250 | Buffalo city (north-northeast 4) | 1,425 |
| 251 | West Seneca CDP (west-northwest 2) | 1,374 |
| 252 | Cheektowaga CDP (west-northwest 1) | 1,332 |
| 253 | Buffalo city (south-southeast 9) | 1,271 |
| 254 | Buffalo city (east-southeast 1) | 1,120 |
| 255 | Unincorporated (east-northeast 3) | 1,033 |
| 256 | Buffalo city (northeast 8) | 998 |
| 257 | Buffalo city (south-southwest 2) | 818 |
| 258 | Buffalo city (north-northeast 1) | 737 |
| 259 | Unincorporated (south-southwest 6) | 583 |
| 260 | Unincorporated (northeast) | 26 |